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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STXBP1
All Species:
41.52
Human Site:
S83
Identified Species:
65.24
UniProt:
P61764
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61764
NP_001027392.1
594
67569
S83
L
I
T
P
S
E
K
S
V
H
S
L
I
S
D
Chimpanzee
Pan troglodytes
XP_001152683
595
67000
S83
L
L
S
P
T
E
K
S
V
Q
A
L
I
K
D
Rhesus Macaque
Macaca mulatta
XP_001095617
580
66142
S69
L
I
T
P
S
E
K
S
V
H
S
L
I
S
D
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q64324
593
66339
S83
L
L
S
P
T
E
K
S
V
Q
A
L
I
A
D
Rat
Rattus norvegicus
P61765
594
67550
S83
L
I
T
P
S
E
K
S
V
H
S
L
I
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508183
589
67400
S69
L
I
T
P
S
E
K
S
V
H
S
L
I
S
D
Chicken
Gallus gallus
Q6R748
594
67454
S83
L
I
T
P
S
E
K
S
V
H
S
L
I
S
D
Frog
Xenopus laevis
NP_001093335
595
67691
S83
L
I
T
P
S
E
K
S
V
H
S
L
I
S
D
Zebra Danio
Brachydanio rerio
NP_001020353
591
67111
S83
L
I
T
P
T
D
K
S
V
Q
T
L
I
N
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07327
597
67832
S94
L
I
T
P
S
D
E
S
V
R
G
L
I
R
D
Honey Bee
Apis mellifera
XP_396375
585
66573
S83
L
I
T
P
C
N
S
S
V
Q
K
L
I
E
D
Nematode Worm
Caenorhab. elegans
P34815
673
76715
A163
I
Y
L
I
A
P
T
A
E
S
I
D
K
L
I
Sea Urchin
Strong. purpuratus
NP_999834
593
68046
N80
I
I
Q
P
N
E
K
N
I
L
Q
L
I
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZ77
662
75299
N98
F
I
Q
P
T
E
E
N
V
T
A
F
L
S
D
Baker's Yeast
Sacchar. cerevisiae
P30619
724
83462
N81
I
L
E
P
T
K
Y
N
I
N
C
I
D
A
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.8
97.6
N.A.
N.A.
62.7
100
N.A.
93.4
97.9
92.4
86.5
N.A.
63.4
63.9
52.1
60.9
Protein Similarity:
100
81.1
97.6
N.A.
N.A.
80.6
100
N.A.
96.1
99.4
97.9
94.6
N.A.
78
79.6
67.4
77.7
P-Site Identity:
100
60
100
N.A.
N.A.
60
100
N.A.
100
100
100
66.6
N.A.
66.6
60
0
46.6
P-Site Similarity:
100
86.6
100
N.A.
N.A.
93.3
100
N.A.
100
100
100
93.3
N.A.
80
60
20
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.2
22.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.2
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
7
0
0
20
0
0
20
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
0
0
0
0
14
0
0
0
0
0
7
7
0
94
% D
% Glu:
0
0
7
0
0
67
14
0
7
0
0
0
0
7
0
% E
% Phe:
7
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
40
0
0
0
0
0
% H
% Ile:
20
74
0
7
0
0
0
0
14
0
7
7
80
0
7
% I
% Lys:
0
0
0
0
0
7
67
0
0
0
7
0
7
7
0
% K
% Leu:
74
20
7
0
0
0
0
0
0
7
0
80
7
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
7
0
20
0
7
0
0
0
7
0
% N
% Pro:
0
0
0
94
0
7
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
14
0
0
0
0
0
0
27
7
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
7
0
0
0
7
0
% R
% Ser:
0
0
14
0
47
0
7
74
0
7
40
0
0
47
0
% S
% Thr:
0
0
60
0
34
0
7
0
0
7
7
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
80
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _